Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 1/20 | 0.38 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | USP19 | O94966 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634464 | 1.00 | PER2 (0.38) | PER2CRY2PRMT5WDR77USP19 | |
| SCHEMBL29634485 | 0.86 | PRMT5 (0.39) | PER2CRY2PRMT5WDR77 | |
| SCHEMBL29634478 | 0.86 | PRMT5 (0.39) | PER2CRY2PRMT5WDR77 | |
| SCHEMBL29634477 | 0.83 | — | — | |
| SCHEMBL29634481 | 0.83 | — | — | |
| SCHEMBL29634382 | 0.74 | ALDH1A1 (0.43) | — | |
| SCHEMBL29634355 | 0.74 | ALDH1A1 (0.43) | — | |
| SCHEMBL28767615 | 0.74 | ALDH1A1 (0.43) | — | |
| SCHEMBL28767673 | 0.71 | — | — | |
| SCHEMBL28767612 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556304-B | Nitroimidazole medicine and preparation method and application thereof | 华创合成制药股份有限公司 | 2022-06-03 | — | — | CN | disclosed |