SCHEMBL2963439

SCHEMBL2963439

Cc1cccc(I)c1C(=O)NC(C)(C)CS(C)(=O)=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.34
DGAT2 Q96PD7 1/20 0.34
POLB P06746 2/20 0.33
ALDH1A1 P00352 2/20 0.33
SSTR4 P31391 3/20 0.32
ITGB2 P05107 1/20 0.32
ICAM1 P05362 1/20 0.32
ITGAL P20701 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
F2R P25116 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
ATM Q13315 2/20 0.31
CNR2 P34972 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15132760 0.80 GAA (0.46) KMT2APOLBL3MBTL1GAAMAPT
SCHEMBL2963051 0.80 SMN1; SMN2 (0.36) KMT2APOLBSSTR4ITGB2ICAM1
SCHEMBL6744852 0.79 MEN1 (0.39) KMT2APOLBALDH1A1L3MBTL1MAPT
SCHEMBL27651311 0.78 KMT2A (0.34) KMT2APOLBSSTR4ITGB2ICAM1
SCHEMBL14076847 0.78 MAPT (0.35) ALDH1A1L3MBTL1GAAMAPTPKM
Flubendiamide SCHEMBL27362 0.76 EPHX2 (0.36) ALDH1A1L3MBTL1GAAMAPTNPC1
Flubendiamide SCHEMBL4054589 0.76 EPHX2 (0.36) ALDH1A1L3MBTL1GAAMAPTNPC1
SCHEMBL15850708 0.76 RXFP1 (0.37) ALDH1A1L3MBTL1GAAMAPTNPC1
Flubendiamide SCHEMBL15798517 0.75 EPHX2 (0.35) ALDH1A1L3MBTL1GAAMAPTNPC1
SCHEMBL1886993 0.75 PPARG (0.37) PKMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1698619-B1 PROCESS FOR PRODUCING 2-HALOGENOBENZAMIDE COMPOUND NIHON NOHYAKU CO LTD (JP) 2013-11-20 EP disclosed
US-7763750-B2 Process for producing 2-halogenobenzamide compound NIHON NOHYAKU CO., LTD. (JP) 2010-07-27 US disclosed
US-20070293701-A1 Process for Producing 2-Halogenobenzamide Compound NIHON NOHYAKU CO., LTD. (JP) 2007-12-20 US disclosed
EP-1698619-A1 PROCESS FOR PRODUCING 2-HALOGENOBENZAMIDE COMPOUND Nihon Nohyaku Co., Ltd. (JP) 2006-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070293701-A1 Process for Producing 2-Halogenobenzamide Compound TYR, CBR3, TH KMT2A 286/4885DGAT2 1176/4885POLB 886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.