Flubendiamide

Flubendiamide

SCHEMBL4054589

Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)ccc1NC(=O)c1cccc(I)c1C(=O)NC(C)(C)CS(C)(=O)=O.Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)ccc1NC(=O)c1cccc(I)c1C(=O)NC(C)(C)CS(C)(=O)=O

nearest known ligand 0.36

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.36
ALDH1A1 P00352 2/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.35
NPC1 O15118 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
RXFP1 Q9HBX9 4/20 0.35
GAA P10253 2/20 0.35
P2RX1 P51575 1/20 0.34
NR1H4 Q96RI1 2/20 0.33
PLA2G7 Q13093 1/20 0.33
CCR8 P51685 1/20 0.33
TP53 P04637 1/20 0.33
PPARG P37231 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flubendiamide SCHEMBL27362 1.00 EPHX2 (0.36) EPHX2ALDH1A1LMNAMAPTNPC1
Flubendiamide SCHEMBL29369179 1.00 EPHX2 (0.36) EPHX2ALDH1A1LMNAMAPTNPC1
Flubendiamide SCHEMBL15798517 0.99 EPHX2 (0.35) EPHX2ALDH1A1LMNAMAPTNPC1
SCHEMBL13121150 0.96 MAPT (0.34) EPHX2ALDH1A1LMNAMAPTNPC1
SCHEMBL1886992 0.96 EPHX2 (0.36) EPHX2ALDH1A1LMNAMAPTNPC1
SCHEMBL1886993 0.94 PPARG (0.37) LMNARAB9AHSD17B10RXFP1P2RX1
SCHEMBL13612662 0.93 RXFP1 (0.36) EPHX2ALDH1A1LMNAMAPTNPC1
SCHEMBL15850708 0.93 RXFP1 (0.37) ALDH1A1LMNAMAPTNPC1ALOX15
SCHEMBL14076847 0.93 MAPT (0.35) ALDH1A1LMNAMAPTNPC1ALOX15
SCHEMBL12996758 0.93 ALDH1A1 (0.38) EPHX2ALDH1A1LMNAMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009117621-A1 PEST CONTROL COMPOSITIONS AND METHODS TYRATECH, INC. (US) 2009-09-24 WO disclosed