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SCHEMBL1886993

SCHEMBL1886993

Cc1ccc(C(F)(C(F)(F)F)C(F)(F)F)cc1NC(=O)c1cccc(I)c1C(=O)NC(C)(C)CS(C)(=O)=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 1/20 0.37
▸ RAF1 P04049 4/20 0.36
▸ BRAF P15056 3/20 0.35
▸ PDGFRB P09619 1/20 0.35
▸ PDGFRA P16234 1/20 0.35
▸ KDR P35968 1/20 0.35
▸ RXFP1 Q9HBX9 3/20 0.34
▸ LMNA P02545 3/20 0.34
▸ KIT P10721 2/20 0.34
▸ TSHR P16473 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ P2RX1 P51575 1/20 0.34
▸ TAS2R14 Q9NYV8 1/20 0.34
▸ CSF1R P07333 1/20 0.34
▸ ESR1 P03372 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ PLA2G7 Q13093 1/20 0.33
▸ LCK P06239 1/20 0.33
▸ SRC P12931 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19362074 0.96 PPARG (0.35) PPARGRAF1BRAFPDGFRBPDGFRA
Flubendiamide SCHEMBL27362 0.94 EPHX2 (0.36) PPARGRXFP1LMNARAB9AHSD17B10
Flubendiamide SCHEMBL4054589 0.94 EPHX2 (0.36) PPARGRXFP1LMNARAB9AHSD17B10
Flubendiamide SCHEMBL29369179 0.94 EPHX2 (0.36) PPARGRXFP1LMNARAB9AHSD17B10
Flubendiamide SCHEMBL15798517 0.93 EPHX2 (0.35) PPARGRXFP1LMNARAB9AHSD17B10
SCHEMBL13121150 0.90 MAPT (0.34) RXFP1LMNARAB9AHSD17B10P2RX1
SCHEMBL1886992 0.90 EPHX2 (0.36) RXFP1LMNARAB9AHSD17B10P2RX1
SCHEMBL13612662 0.86 RXFP1 (0.36) PPARGRXFP1LMNARAB9AHSD17B10
SCHEMBL15850708 0.86 RXFP1 (0.37) RAF1RXFP1LMNARAB9AHSD17B10
SCHEMBL14076847 0.86 MAPT (0.35) RXFP1LMNARAB9AHSD17B10P2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2303007-B1 PESTICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2016-02-10 — — EP claimed
US-20080206345-A1 Abamectin, lambda-cyhalothrin and lufenuron; nematocides SYNGENTA CROP PROTECTION, INC. (US) 2008-08-28 — — US claimed
US-12161117-B2 Agrochemical combinations UPL LTD (IN) 2024-12-10 — — US disclosed
US-20240315243-A1 A COMBINATION OF FLUBENDIAMIDE AND SEAWEED EXTRACT PI INDUSTRIES LTD. (IN) 2024-09-26 — — US disclosed
US-11812748-B2 Pesticidal combinations UPL LTD (IN) 2023-11-14 — — US disclosed
WO-2022269523-A1 A COMBINATION OF FLUBENDIAMIDE AND SEAWEED EXTRACT PI INDUSTRIES LTD. (IN) 2022-12-29 — — WO disclosed
CN-111225562-B Active ingredient combinations having insecticidal/acaricidal properties 拜耳公司 2022-08-02 — — CN disclosed
CN-109430285-B Pesticide composition 先正达参股股份有限公司 2022-05-03 — — CN disclosed
US-11191271-B2 Active compound combinations having insecticidal/acaricidal properties BAYER AKTIENGESELLSCHAFT (DE) 2021-12-07 — — US disclosed
EP-2303007-B2 PESTICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2021-10-13 — — EP disclosed
US-20210127680-A1 NOVEL AGROCHEMICAL COMBINATIONS UPL LTD (IN) 2021-05-06 — — US disclosed
US-8329310-B2 Insecticidal composition and method ZELAM LIMITED (NZ) 2012-12-11 — — US disclosed
EP-2437597-A2 COMBINATIONS OF FLUBENDIAMIDES AND USEFUL ORGANISMS Bayer CropScience AG (DE) 2012-04-11 — — EP disclosed
US-20110105576-A1 PESTICIDAL COMBINATIONS SYNGENTA CROP PROTECTION, INC. (US) 2011-05-05 — — US disclosed
US-20100310518-A1 Combinations of Flubendiamide and Beneficial Species BAYER CROPSCIENCE AG (DE) 2010-12-09 — — US disclosed
WO-2010139408-A2 COMBINATIONS OF FLUBENDIAMIDES AND USEFUL ORGANISMS BAYER CROPSCIENCE AG (DE) 2010-12-09 — — WO disclosed
US-20100144725-A1 PESTICIDAL COMBINATIONS SYNGENTA CROP PROTECTION, INC. (US) 2010-06-10 — — US disclosed
US-20080287294-A1 Method of Mollusc Control SYNGENTA CROP PROTECTION, INC. (US) 2008-11-20 — — US disclosed
US-20080206345-A1 Abamectin, lambda-cyhalothrin and lufenuron; nematocides SYNGENTA CROP PROTECTION, INC. (US) 2008-08-28 — — US disclosed
US-20080194599-A1 Method of Mollusc Control SYNGENTA CROP PROTECTION, INC. (US) 2008-08-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194599-A1 Method of Mollusc Control PTMA, PIR, FLNB PPARG 2062/4885RAF1 2093/4885BRAF 981/4885
US-20080206345-A1 Abamectin, lambda-cyhalothrin and lufenuron; nematocides ATL3, RPL30, MLN PPARG 3682/4885RAF1 4450/4885BRAF 3776/4885
US-11812748-B2 Pesticidal combinations DDT, BCHE, QDPR PPARG 1126/4885RAF1 3580/4885BRAF 2022/4885
US-20240315243-A1 A COMBINATION OF FLUBENDIAMIDE AND SEAWEED EXTRACT ACHE, DDT, ARF4 PPARG 3068/4885RAF1 4533/4885BRAF 3170/4885
US-12161117-B2 Agrochemical combinations DDT, ACHE, BCHE PPARG 2924/4885RAF1 4180/4885BRAF 3934/4885
US-20210127680-A1 NOVEL AGROCHEMICAL COMBINATIONS DDT, ACHE, UCHL3 PPARG 3602/4885RAF1 4138/4885BRAF 4031/4885
US-20100144725-A1 PESTICIDAL COMBINATIONS PIR, TPI1, PFN1 PPARG 2949/4885RAF1 1607/4885BRAF 1101/4885
US-20080287294-A1 Method of Mollusc Control TBCB, DDT, TUBB2B PPARG 1099/4885RAF1 4878/4885BRAF 4609/4885
US-11191271-B2 Active compound combinations having insecticidal/acaricidal properties ACHE, CYP51A1, ACAT1 PPARG 2838/4885RAF1 4250/4885BRAF 4517/4885
US-20110105576-A1 PESTICIDAL COMBINATIONS MLX, CLPX, CYP4X1 PPARG 2637/4885RAF1 3558/4885BRAF 2673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.