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SCHEMBL29634488

SCHEMBL29634488

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)O)C(C)C

nearest known ligand 0.78

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CALCR P30988 3/20 0.75
▸ GLP1R P43220 16/20 0.74
▸ GCGR P47871 9/20 0.74
▸ GIPR P48546 6/20 0.74
▸ CCKBR P32239 4/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30011968 0.98 GLP1R (0.79) CALCRGLP1RGCGRGIPRCCKBR
SCHEMBL31099269 0.98 GLP1R (0.79) CALCRGLP1RGCGRGIPRCCKBR
SCHEMBL31139954 0.96 GLP1R (0.79) CALCRGLP1RGCGRGIPRCCKBR
SCHEMBL30205160 0.96 GLP1R (0.81) CALCRGLP1RGCGRGIPRCCKBR
SCHEMBL30460356 0.96 GLP1R (0.80) CALCRGLP1RGCGRGIPRCCKBR
SCHEMBL29576071 0.96 GLP1R (0.80) CALCRGLP1RGCGRGIPRCCKBR
SCHEMBL30473764 0.96 GLP1R (0.80) CALCRGLP1RGCGRGIPRCCKBR
SCHEMBL30645490 0.96 GLP1R (0.80) CALCRGLP1RGCGRGIPRCCKBR
SCHEMBL30181569 0.95 GLP1R (0.73) CALCRGLP1RGCGRGIPR
SCHEMBL30181709 0.95 GLP1R (0.73) CALCRGLP1RGCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113350488-B Application of oral hypoglycemic peptide OHP in preparation of medicine for resisting neurodegenerative diseases 中国药科大学 2023-07-14 — — CN claimed
CN-111905097-B Application of oral glycopeptide lowering in preparation of medicine for treating or preventing diabetes complicated with cardiovascular diseases 中国药科大学 2022-06-28 — — CN claimed
CN-113350488-B Application of oral hypoglycemic peptide OHP in preparation of medicine for resisting neurodegenerative diseases 中国药科大学 2023-07-14 — — CN disclosed
CN-111905097-B Application of oral glycopeptide lowering in preparation of medicine for treating or preventing diabetes complicated with cardiovascular diseases 中国药科大学 2022-06-28 — — CN disclosed
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