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SCHEMBL30011968

SCHEMBL30011968

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.82

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 16/20 0.79
▸ GCGR P47871 9/20 0.79
▸ GIPR P48546 6/20 0.78
▸ CALCR P30988 3/20 0.71
▸ CCKBR P32239 3/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31099269 1.00 GLP1R (0.79) GLP1RGCGRGIPRCALCRCCKBR
SCHEMBL31139954 0.98 GLP1R (0.79) GLP1RGCGRGIPRCALCRCCKBR
SCHEMBL30645490 0.98 GLP1R (0.80) GLP1RGCGRGIPRCALCRCCKBR
SCHEMBL30205160 0.98 GLP1R (0.81) GLP1RGCGRGIPRCALCRCCKBR
SCHEMBL30460356 0.98 GLP1R (0.80) GLP1RGCGRGIPRCALCRCCKBR
SCHEMBL30473764 0.98 GLP1R (0.80) GLP1RGCGRGIPRCALCRCCKBR
SCHEMBL29576071 0.98 GLP1R (0.80) GLP1RGCGRGIPRCALCRCCKBR
SCHEMBL29634488 0.98 CALCR (0.75) GLP1RGCGRGIPRCALCRCCKBR
SCHEMBL30422794 0.97 GLP1R (0.74) GLP1RGCGRGIPRCALCR
SCHEMBL31139990 0.97 GLP1R (0.77) GLP1RGCGRGIPRCALCRCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115232200-B Long-acting Exendin-4 analogue and application thereof 北京博康健基因科技有限公司 2023-06-27 — — CN disclosed
CN-115232200-A Long-acting Exendin-4 analogue and application thereof 北京博康健基因科技有限公司 2022-10-25 — — CN disclosed
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