Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 3/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.56 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PDE5A | O76074 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 3/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233252 | 1.00 | HTT (0.58) | HTTEGFRKDM4CPOLBNR2F2 | |
| SCHEMBL11827284 | 0.83 | STAT1 (0.62) | HTTKDM4CPOLBGALR3MEN1 | |
| SCHEMBL16781105 | 0.82 | LMNA (0.58) | HTTEGFRPOLBNR2F2MEN1 | |
| SCHEMBL7746233 | 0.82 | CNR1 (0.54) | KDM4CGALR3MAPTALDH1A1RAB9A | |
| SCHEMBL10873653 | 0.81 | KDM4C (0.60) | HTTEGFRKDM4CPOLBGALR3 | |
| SCHEMBL18786736 | 0.81 | HTT (0.56) | HTTEGFRPOLBNR2F2MEN1 | |
| SCHEMBL783719 | 0.81 | KDM4C (0.72) | HTTEGFRKDM4CNR2F2GALR3 | |
| SCHEMBL30983851 | 0.81 | KDM4C (0.72) | HTTEGFRKDM4CNR2F2GALR3 | |
| SCHEMBL20061544 | 0.81 | AURKA (0.59) | HTTEGFRPOLBNR2F2MEN1 | |
| SCHEMBL22307619 | 0.81 | CYP1A2 (0.58) | MEN1KMT2ALMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3514149-B1 | HETEROCYCLIC AMIDE COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2022-05-18 | — | — | EP | disclosed |