Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24408823 | 1.00 | HTR2C (0.35) | HTR2CALDH1A1HPGDHSD17B10HTR2B | |
| SCHEMBL24408811 | 0.78 | — | — | |
| SCHEMBL29634699 | 0.75 | ACACB (0.35) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL29634730 | 0.70 | CHRNB2 (0.43) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL23811371 | 0.70 | CHRNB2 (0.43) | ALDH1A1HPGD | |
| SCHEMBL13161926 | 0.70 | CHRNB2 (0.43) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL28499917 | 0.68 | HTR2C (0.50) | HTR2CHTR2B | |
| SCHEMBL24408815 | 0.68 | IRAK4 (0.34) | — | |
| Hydrochloric Acid SCHEMBL10502304 | 0.67 | HTR2C (0.49) | HTR2CHTR2B | |
| SCHEMBL24408805 | 0.67 | CHRNB2 (0.43) | HTR2CALDH1A1HPGDHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022095971-A1 | SPIRO HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海医药集团股份有限公司 | 2022-05-12 | — | — | WO | disclosed |