Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | FABP6 | P51161 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21381457 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HTTGAAPKMCSF1R | |
| SCHEMBL21391367 | 0.84 | KIT (0.68) | ALDH1A1HTTGAACSF1RPDGFRB | |
| SCHEMBL21385153 | 0.82 | KIT (0.66) | ALDH1A1HTTGAACSF1RPDGFRB | |
| SCHEMBL29634986 | 0.82 | KIT (0.66) | ALDH1A1HTTGAACSF1RPDGFRB | |
| SCHEMBL21391366 | 0.81 | KIT (0.57) | ALDH1A1HTTGAAPKMCSF1R | |
| SCHEMBL21391420 | 0.81 | KIT (0.57) | ALDH1A1HTTGAAPKMCSF1R | |
| SCHEMBL21391364 | 0.80 | KIT (0.57) | ALDH1A1HTTGAAPKMCSF1R | |
| SCHEMBL21391361 | 0.80 | KIT (0.57) | ALDH1A1HTTGAAPKMCSF1R | |
| SCHEMBL21391407 | 0.79 | KIT (0.55) | ALDH1A1HTTGAACSF1RPDGFRB | |
| SCHEMBL21391402 | 0.79 | KIT (0.55) | ALDH1A1HTTGAACSF1RPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110283160-B | PDGFR kinase inhibitor | 中国科学院合肥物质科学研究院 | 2022-04-29 | — | — | CN | disclosed |