Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.37 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19866691 | 1.00 | CSNK1A1 (0.38) | CSNK1A1CLK4ROCK2ROCK1CDC42BPA | |
| SCHEMBL16668748 | 0.76 | CSNK1A1 (0.45) | CSNK1A1CLK4NOS3NOS1NOS2 | |
| SCHEMBL22549256 | 0.75 | LRRK2 (0.36) | ROCK2ROCK1CDC42BPACDC42BPBALDH1A1 | |
| SCHEMBL2767503 | 0.75 | NOS3 (0.56) | CSNK1A1CLK4NOS3NOS1NOS2 | |
| SCHEMBL30971228 | 0.74 | CSNK1A1 (0.44) | CSNK1A1CLK4NOS3NOS1NOS2 | |
| SCHEMBL1457800 | 0.74 | CSNK1A1 (0.44) | CSNK1A1CLK4NOS3NOS1NOS2 | |
| SCHEMBL24048664 | 0.72 | NOS3 (0.58) | NOS3NOS1NOS2KDM4EGAA | |
| SCHEMBL31420102 | 0.71 | GAA (0.42) | CLK4NOS3NOS1NOS2GAA | |
| SCHEMBL21011621 | 0.71 | CSNK1A1 (0.41) | CSNK1A1CLK4NOS3NOS1NOS2 | |
| SCHEMBL31512102 | 0.71 | CYP11B1 (0.44) | CSNK1A1CLK4NPC1RAB9AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563091-B | FGFR4 inhibitor and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2022-04-29 | — | — | CN | disclosed |