Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GALK1 | P51570 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 4/20 | 0.40 |
| ▸ | NOS2 | P35228 | 4/20 | 0.40 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24048664 | 0.77 | NOS3 (0.58) | GAAKMT2ANOS3NOS2NOS1 | |
| SCHEMBL26288012 | 0.77 | SLC6A2 (0.36) | GAAKMT2AMAPTAPAF1TDP2 | |
| SCHEMBL29739386 | 0.72 | — | — | |
| SCHEMBL207537 | 0.72 | — | — | |
| SCHEMBL558662 | 0.71 | — | — | |
| SCHEMBL31729640 | 0.71 | — | — | |
| SCHEMBL29635160 | 0.71 | CSNK1A1 (0.38) | GAAMAPTL3MBTL1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL9455853 | 0.71 | GAA (0.35) | GAAKMT2AMAPTAPAF1TDP2 | |
| SCHEMBL9455820 | 0.71 | DHFR (0.38) | GAAKMT2AMAPTAPAF1TDP2 | |
| SCHEMBL19866691 | 0.71 | CSNK1A1 (0.38) | GAAMAPTL3MBTL1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119562812-A | Substituted N- (pyridin-2-yl) acetamide derivatives as CDK12/13 inhibitors | 奥里吉恩肿瘤学有限公司 | 2025-03-04 | — | — | CN | disclosed |