Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.54 |
| ▸ | TFPI | P10646 | 1/20 | 0.53 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.52 |
| ▸ | VIPR2 | P41587 | 5/20 | 0.51 |
| ▸ | NPY4R | P50391 | 4/20 | 0.51 |
| ▸ | VIPR1 | P32241 | 3/20 | 0.51 |
| ▸ | NPY1R | P25929 | 3/20 | 0.51 |
| ▸ | NPY2R | P49146 | 3/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30483971 | 0.88 | NPY4R (0.55) | VIPR2NPY4RVIPR1NPY1RNPY2R | |
| SCHEMBL29635274 | 0.87 | TFPI (0.55) | OPRL1TFPIIL23RNPY4RNPY1R | |
| SCHEMBL29364983 | 0.87 | TFPI (0.63) | TFPIVIPR2VIPR1 | |
| SCHEMBL31411175 | 0.86 | TFPI (0.57) | OPRL1TFPIIL23RVIPR2NPY4R | |
| SCHEMBL31370896 | 0.86 | TFPI (0.57) | OPRL1TFPIIL23RVIPR2NPY4R | |
| SCHEMBL30974623 | 0.85 | TFPI (0.63) | TFPIVIPR2VIPR1KEAP1 | |
| SCHEMBL30176485 | 0.85 | VIPR2 (0.61) | TFPIVIPR2NPY4RVIPR1NPY1R | |
| SCHEMBL29373965 | 0.84 | TFPI (0.60) | TFPIIL23RVIPR2VIPR1KEAP1 | |
| SCHEMBL29512407 | 0.84 | NPY4R (0.58) | TFPIIL23RVIPR2NPY4RVIPR1 | |
| SCHEMBL29663842 | 0.84 | TFPI (0.57) | TFPINPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240336652-A1 | Peptide compounds targeting PD-1 receptor as well as preparation and applications thereof | UNIV NANTONG (CN) | 2024-10-10 | — | — | US | disclosed |
| WO-2022257831-A1 | POLYPEPTIDE COMPOUNDS USING PD-1 RECEPTORS AS TARGETS, PREPARATION METHOD THEREFOR AND USE THEREOF | 南通大学 | 2022-12-15 | — | — | WO | disclosed |
| CN-113416232-B | Polypeptide compounds with PD-1 receptor as target spot, preparation method and application thereof | 南通大学 | 2022-06-03 | — | — | CN | disclosed |