SCHEMBL29373965

SCHEMBL29373965

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.60
▸ KEAP1 Q14145 1/20 0.58
▸ F2 P00734 2/20 0.57
▸ VIPR2 P41587 6/20 0.57
▸ VIPR1 P32241 4/20 0.57
▸ IL23R Q5VWK5 2/20 0.53
▸ ECE1 P42892 1/20 0.53
▸ GLP1R P43220 1/20 0.53
▸ MUS81 Q96NY9 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30262251 0.92 TFPI (0.63) TFPIF2VIPR2VIPR1IL23R
SCHEMBL29686242 0.89 KISS1R (0.62) TFPIF2VIPR2VIPR1
SCHEMBL29742337 0.89 TFPI (0.58) TFPIF2VIPR2VIPR1IL23R
SCHEMBL31437676 0.89 NPY4R (0.60) TFPIVIPR2VIPR1
SCHEMBL30176441 0.89 TFPI (0.64) TFPIKEAP1VIPR2VIPR1ECE1
SCHEMBL30220503 0.89 TFPI (0.66) TFPIKEAP1VIPR2VIPR1ECE1
SCHEMBL30168722 0.89 TFPI (0.59) TFPIF2VIPR2VIPR1IL23R
SCHEMBL19221753 0.88 TFPI (0.59) TFPIF2IL23R
SCHEMBL30900764 0.88 TFPI (0.65) TFPIVIPR2VIPR1ECE1GLP1R
SCHEMBL30900785 0.88 TFPI (0.65) TFPIVIPR2VIPR1ECE1GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023230464-A2 A MURINE MODEL TO TEST THE EFFECT OF PKP2 MUTATIONS ON LIVING ADULT HEARTS AND USES THEREOF NEW YORK UNIVERSITY (US) 2023-11-30 — — WO claimed
US-20260091017-A1 TREATMENTS FOR INFLAMMATION AUCKLAND UNISERVICES LTD (NZ) 2026-04-02 — — US disclosed
EP-4677087-A1 NOVEL TREATMENTS FOR OCULAR DISORDERS Glaukos Corporation (US) 2026-01-14 — — EP disclosed
US-20250352508-A1 PREVENTION AND TREATMENT OF POST-ACUTE INFECTION SYNDROMES INFLAMMX THERAPEUTICS INC (US) 2025-11-20 — — US disclosed
US-20250136987-A1 CHANNEL MODULATORS INFLAMMX THERAPEUTICS, INC. 2025-05-01 — — US disclosed
US-20250127851-A1 CYTOKINE MODULATION INFLAMMX THERAPEUTICS, INC. 2025-04-24 — — US disclosed
US-12226393-B2 Neuroprotective compounds for amyotrophic lateral sclerosis THE JOHNS HOPKINS UNIVERSITY (US) 2025-02-18 — — US disclosed
EP-4491184-A2 CHANNEL MODULATORS Auckland Uniservices Limited (NZ) 2025-01-15 — — EP disclosed
EP-3183346-B1 CHANNEL MODULATORS AUCKLAND UNISERVICES LTD (NZ) 2024-10-23 — — EP disclosed
US-20240299440-A1 NOVEL TREATMENTS FOR OCULAR DISORDERS GLAUKOS CORPORATION 2024-09-12 — — US disclosed
US-11717506-B2 Neuroprotective compounds for amyotrophic lateral sclerosis THE JOHNS HOPKINS UNIVERSITY (US) 2023-08-08 — — US disclosed
US-20230174980-A1 CHANNEL MODULATORS INFLAMMX THERAPEUTICS, INC. 2023-06-08 — — US disclosed
US-20230123615-A1 METHODS OF TREATMENT AND NOVEL CONSTRUCTS INFLAMMX THERAPEUTICS, INC. 2023-04-20 — — US disclosed
US-11466069-B2 Methods of treatment and novel constructs AUCKLAND UNISERVICES LIMITED (NZ) 2022-10-11 — — US disclosed
US-20220288163-A1 CYTOKINE MODULATION INFLAMMX THERAPEUTICS, INC. 2022-09-15 — — US disclosed
US-11401516-B2 Channel modulators AUCKLAND UNISERVICES LIMITED (NZ) 2022-08-02 — — US disclosed
US-11344603-B2 Cytokine modulation AUCKLAND UNISERVICES LIMITED (NZ) 2022-05-31 — — US disclosed
EP-3958886-A1 COMPOSITIONS AND METHODS FOR PROTECTING EPITHELIAL AND BARRIER INTEGRITY Ocunexus Therapeutics, Inc. (US) 2022-03-02 — — EP disclosed
CN-114010788-A Channel modulators 奥克兰联合服务有限公司 2022-02-08 — — CN disclosed
CN-114025786-A Compositions and methods for protecting epithelial and barrier integrity 欧耐柯萨斯医疗有限公司 2022-02-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174980-A1 CHANNEL MODULATORS GJB2, GJA1, P2RX2 TFPI 2323/4885KEAP1 1638/4885F2 4487/4885
US-20240299440-A1 NOVEL TREATMENTS FOR OCULAR DISORDERS GJB2, GJA1, CX3CR1 TFPI 3415/4885KEAP1 1593/4885F2 4503/4885
US-20260091017-A1 TREATMENTS FOR INFLAMMATION P2RX7, NLRP3, PYCARD TFPI 293/4885KEAP1 541/4885F2 3755/4885
US-20250352508-A1 PREVENTION AND TREATMENT OF POST-ACUTE INFECTION SYNDROMES NLRP3, GJA1, PYCARD TFPI 1780/4885KEAP1 433/4885F2 3585/4885
US-11717506-B2 Neuroprotective compounds for amyotrophic lateral sclerosis NLN, SMN1; SMN2, SOD1 TFPI 3000/4885KEAP1 445/4885F2 4780/4885
US-12226393-B2 Neuroprotective compounds for amyotrophic lateral sclerosis NLN, SMN1; SMN2, SOD1 TFPI 3000/4885KEAP1 445/4885F2 4780/4885
US-20250127851-A1 CYTOKINE MODULATION TNF, IL2, IL1B TFPI 1618/4885KEAP1 3047/4885F2 3537/4885
US-20220288163-A1 CYTOKINE MODULATION TNF, IL2, IL1B TFPI 1618/4885KEAP1 3047/4885F2 3537/4885
US-11401516-B2 Channel modulators GJB2, GJA1, P2RX2 TFPI 2323/4885KEAP1 1638/4885F2 4487/4885
US-11344603-B2 Cytokine modulation TNF, IL2, IL1B TFPI 1618/4885KEAP1 3047/4885F2 3537/4885
US-20250136987-A1 CHANNEL MODULATORS GJB2, GJA1, P2RX2 TFPI 2323/4885KEAP1 1638/4885F2 4487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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