Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | ULK1 | O75385 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30421024 | 1.00 | HDAC1 (0.36) | HDAC1HDAC6HDAC5ULK1DGAT1 | |
| SCHEMBL22042756 | 1.00 | HDAC1 (0.36) | HDAC1HDAC6HDAC5ULK1DGAT1 | |
| Ether SCHEMBL22042754 | 0.93 | DGAT1 (0.36) | HDAC1HDAC6HDAC5ULK1DGAT1 | |
| SCHEMBL30969065 | 0.89 | HDAC1 (0.41) | HDAC1HDAC6HDAC5HDAC8PDGFRB | |
| SCHEMBL22042711 | 0.89 | HDAC1 (0.41) | HDAC1HDAC6HDAC5HDAC8PDGFRB | |
| SCHEMBL29635363 | 0.89 | HDAC1 (0.41) | HDAC1HDAC6HDAC5HDAC8PDGFRB | |
| SCHEMBL22042748 | 0.86 | PDE10A (0.43) | HDAC1HDAC6HDAC5CHEK1PDE10A | |
| SCHEMBL30969081 | 0.86 | PDE10A (0.43) | HDAC1HDAC6HDAC5CHEK1PDE10A | |
| SCHEMBL29635376 | 0.86 | PDE10A (0.43) | HDAC1HDAC6HDAC5CHEK1PDE10A | |
| SCHEMBL30151298 | 0.81 | MAPT (0.43) | KMT2AKDM4ESMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112739689-B | Fluorine-containing pyrimidine compound and method for producing same | 优迈特株式会社 | 2022-06-03 | — | — | CN | disclosed |