Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255561 | 1.00 | L3MBTL1 (0.69) | L3MBTL1TDP1KDM4ETTRCYP1A2 | |
| SCHEMBL17394783 | 0.92 | L3MBTL1 (0.61) | L3MBTL1TDP1KDM4ETTRCYP1A2 | |
| SCHEMBL255559 | 0.89 | L3MBTL1 (0.72) | L3MBTL1TDP1KDM4ETTRCYP1A2 | |
| SCHEMBL10263925 | 0.88 | L3MBTL1 (0.76) | L3MBTL1TDP1KDM4ETTRCYP1A2 | |
| SCHEMBL6888665 | 0.86 | L3MBTL1 (0.73) | L3MBTL1TDP1KDM4ECYP1A2CYP2C19 | |
| SCHEMBL4612580 | 0.86 | L3MBTL1 (0.73) | L3MBTL1TDP1KDM4ECYP1A2CYP2C19 | |
| SCHEMBL9148177 | 0.86 | L3MBTL1 (0.73) | L3MBTL1TDP1KDM4ECYP1A2CYP2C19 | |
| SCHEMBL28027719 | 0.86 | L3MBTL1 (0.73) | L3MBTL1TDP1KDM4ECYP1A2CYP2C19 | |
| 1,2-Dipropoxybenzene SCHEMBL578657 | 0.84 | CYP1A2 (0.56) | L3MBTL1TDP1KDM4ECYP1A2CYP2C19 | |
| 1,2-Dipropoxybenzene SCHEMBL29428926 | 0.84 | CYP1A2 (0.56) | L3MBTL1TDP1KDM4ECYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12336981-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2025-06-24 | — | — | US | disclosed |
| US-11547701-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-11279687-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2022-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279687-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNT, NQO1 | L3MBTL1 3643/4885TDP1 4076/4885KDM4E 813/4885 |
| US-12336981-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNMT, NNT | L3MBTL1 3102/4885TDP1 3705/4885KDM4E 1401/4885 |
| US-11547701-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNMT, NQO1 | L3MBTL1 2990/4885TDP1 3665/4885KDM4E 1325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.