Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 7/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | RET | P07949 | 2/20 | 0.50 |
| ▸ | PIM1 | P11309 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | LYN | P07948 | 1/20 | 0.50 |
| ▸ | FER | P16591 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29636022 | 0.77 | LMNA (0.58) | GRIN2BGRIN1PDE3BPDE3ACYP2C19 | |
| SCHEMBL30176559 | 0.72 | PRKD3 (0.64) | GRIN2BGRIN1PRKD3MAP4K4RET | |
| SCHEMBL30176772 | 0.71 | PRKD3 (0.71) | GRIN2BGRIN1PRKD3MAP4K4RET | |
| SCHEMBL30532128 | 0.70 | PRKD3 (0.66) | GRIN2BGRIN1PRKD3MAP4K4RET | |
| SCHEMBL13564022 | 0.69 | PRKD3 (0.61) | PRKD3MAP4K4RETPIM1KDR | |
| SCHEMBL29635977 | 0.69 | PRKD3 (0.55) | GRIN2BGRIN1PRKD3MAP4K4RET | |
| SCHEMBL29636031 | 0.68 | PRKD3 (0.70) | GRIN2BGRIN1PRKD3MAP4K4RET | |
| SCHEMBL30176751 | 0.66 | PRKD3 (0.64) | GRIN2BGRIN1PRKD3MAP4K4RET | |
| SCHEMBL2208549 | 0.66 | PDE3B (1.00) | PRKD3MAP4K4RETPIM1KDR | |
| SCHEMBL30176755 | 0.66 | PRKD3 (0.58) | GRIN2BGRIN1PRKD3MAP4K4RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110062761-B | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2022-05-13 | — | — | CN | disclosed |