Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 18/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 17/20 | 0.58 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28736409 | 1.00 | GRIN2B (0.58) | GRIN2BGRIN1CNR2CNR1 | |
| SCHEMBL20129960 | 0.74 | GRIN1 (1.00) | GRIN2BGRIN1 | |
| SCHEMBL20134182 | 0.73 | GRIN1 (1.00) | GRIN2BGRIN1 | |
| SCHEMBL31008705 | 0.71 | GRIN1 (0.59) | GRIN2BGRIN1CNR2CNR1 | |
| SCHEMBL31533729 | 0.71 | PDE1B (0.66) | — | |
| SCHEMBL27193449 | 0.71 | PDE1B (0.66) | — | |
| SCHEMBL31008752 | 0.71 | GRIN2B (0.68) | GRIN2BGRIN1 | |
| SCHEMBL20130195 | 0.69 | GRIN1 (1.00) | GRIN2BGRIN1 | |
| SCHEMBL29636125 | 0.69 | GRIN1 (1.00) | GRIN2BGRIN1 | |
| SCHEMBL31008690 | 0.69 | GRIN2B (0.65) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989164-B | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-114989164-A | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-110062761-B | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2022-05-13 | — | — | CN | disclosed |