Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 8/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21117369 | 0.84 | PDE4B (0.61) | GRIN1GRIN2BHSD17B10 | |
| SCHEMBL20129909 | 0.81 | PDE1B (0.56) | GRIN1GRIN2BKDM4EMTORALDH1A1 | |
| SCHEMBL29636174 | 0.81 | PDE1B (0.56) | GRIN1GRIN2BKDM4EMTORALDH1A1 | |
| SCHEMBL17242598 | 0.78 | KDM4E (0.70) | KDM4EALDH1A1CASP1HSD17B10USP2 | |
| SCHEMBL34462136 | 0.76 | ALDH1A1 (0.55) | GRIN1GRIN2BKDM4EMTORALDH1A1 | |
| SCHEMBL29722691 | 0.75 | KDM4E (0.56) | KDM4EMTORALDH1A1MEN1MAPT | |
| SCHEMBL21117546 | 0.75 | PDE4B (0.62) | GRIN1GRIN2BHSD17B10 | |
| SCHEMBL20134563 | 0.74 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL18556093 | 0.73 | GRIN1 (0.58) | GRIN1GRIN2BKDM4EMTORALDH1A1 | |
| SCHEMBL29691179 | 0.73 | KDM4E (0.54) | GRIN1GRIN2BKDM4EMTORALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989164-B | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2024-08-13 | — | — | CN | disclosed |