Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28736545 | 1.00 | PDE10A (0.47) | PDE10AALDH1A1LMNAHPGDCYP1A2 | |
| SCHEMBL28736606 | 0.85 | ALDH1A1 (0.56) | PDE10AALDH1A1LMNAHPGDCYP1A2 | |
| SCHEMBL1315514 | 0.84 | PDE10A (0.56) | PDE10AALDH1A1LMNAHPGDCYP1A2 | |
| SCHEMBL1888912 | 0.82 | ALDH1A1 (0.58) | PDE10AALDH1A1LMNAHPGDCYP1A2 | |
| SCHEMBL1882141 | 0.81 | ALDH1A1 (0.61) | PDE10AALDH1A1LMNAHPGDCYP1A2 | |
| SCHEMBL14341082 | 0.80 | PDE10A (0.74) | PDE10AALDH1A1KDM4EL3MBTL1PBRM1 | |
| SCHEMBL16202757 | 0.77 | L3MBTL1 (0.63) | PDE10AALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL30856710 | 0.77 | KDM4E (0.54) | PDE10AALDH1A1HPGDCYP2C9CYP2C19 | |
| SCHEMBL27240665 | 0.77 | KDM4E (0.54) | PDE10AALDH1A1HPGDCYP2C9CYP2C19 | |
| SCHEMBL456449 | 0.77 | CYP2A6 (0.51) | PDE10AALDH1A1HPGDCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110015985-B | 2- (alpha-deuterium-alpha-hydroxy-alpha-aryl/alkyl) aza-aromatic hydrocarbon compound and preparation method and application thereof | 河南师范大学 | 2022-05-13 | — | — | CN | disclosed |