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Sugi Predict / Compounds / SCHEMBL29636362

SCHEMBL29636362

SCHEMBL29636362

CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ EPHA2 P29317 2/20 0.51
▸ NRP1 O14786 1/20 0.47
▸ RAMP3 O60896 11/20 0.46
▸ CALCR P30988 11/20 0.46
▸ NTSR2 O95665 2/20 0.46
▸ NTSR1 P30989 2/20 0.46
▸ SORT1 Q99523 2/20 0.46
▸ PLK1 P53350 1/20 0.44
▸ C5AR1 P21730 1/20 0.43
▸ CXCR4 P61073 1/20 0.43
▸ GRB2 P62993 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29636364 0.98 EPHA2 (0.51) EPHA2NRP1RAMP3CALCRNTSR2
SCHEMBL29636368 0.93 EPHA2 (0.53) EPHA2RAMP3CALCRPLK1C5AR1
SCHEMBL30415970 0.92 NRP1 (0.51) EPHA2NRP1RAMP3CALCRNTSR2
SCHEMBL31313242 0.90 EPHA2 (0.52) EPHA2NRP1RAMP3CALCR
SCHEMBL31031563 0.89 RAMP3 (0.49) EPHA2RAMP3CALCRGRB2
SCHEMBL30320583 0.89 RAMP3 (0.52) EPHA2RAMP3CALCR
SCHEMBL31265322 0.88 EPHA2 (0.50) EPHA2RAMP3CALCRPLK1CXCR4
SCHEMBL29886811 0.88 EPHA2 (0.45) EPHA2NRP1RAMP3CALCRNTSR2
SCHEMBL22872708 0.87 NRP1 (0.54) EPHA2NRP1NTSR2NTSR1SORT1
SCHEMBL31410874 0.87 RAMP3 (0.53) RAMP3CALCRNTSR2NTSR1SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3187508-B1 LYSOSOMAL TARGETING PEPTIDES AND USES THEREOF BIOMARIN PHARM INC (US) 2026-04-22 — — EP disclosed
US-20230241187-A1 Lysosomal Targeting Peptides and Uses Thereof BIOMARIN PHARMACEUTICAL INC. 2023-08-03 — — US disclosed
US-20220354934-A1 Lysosomal Targeting Peptides and Uses Thereof BIOMARIN PHARMACEUTICAL INC. 2022-11-10 — — US disclosed
US-11351231-B2 Lysosomal targeting peptides and uses thereof BIOMARIN PHARMACEUTICAL INC. (US) 2022-06-07 — — US disclosed