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Sugi Predict / Compounds / SCHEMBL29636364

SCHEMBL29636364

SCHEMBL29636364

CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ EPHA2 P29317 2/20 0.51
▸ NRP1 O14786 2/20 0.48
▸ RAMP3 O60896 12/20 0.47
▸ CALCR P30988 12/20 0.47
▸ C5AR1 P21730 1/20 0.45
▸ NTSR2 O95665 1/20 0.44
▸ NTSR1 P30989 1/20 0.44
▸ SORT1 Q99523 1/20 0.44
▸ PLK1 P53350 1/20 0.44
▸ GRB2 P62993 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29636362 0.98 EPHA2 (0.51) EPHA2NRP1RAMP3CALCRC5AR1
SCHEMBL29636368 0.94 EPHA2 (0.53) EPHA2RAMP3CALCRC5AR1PLK1
SCHEMBL31313242 0.91 EPHA2 (0.52) EPHA2NRP1RAMP3CALCR
SCHEMBL30415970 0.91 NRP1 (0.51) EPHA2NRP1RAMP3CALCRNTSR2
SCHEMBL29886811 0.89 EPHA2 (0.45) EPHA2NRP1RAMP3CALCRC5AR1
SCHEMBL22872708 0.89 NRP1 (0.54) EPHA2NRP1NTSR2NTSR1SORT1
SCHEMBL30320583 0.89 RAMP3 (0.52) EPHA2RAMP3CALCR
SCHEMBL30844348 0.88 NPY2R (0.48) NTSR2NTSR1SORT1
SCHEMBL31265322 0.88 EPHA2 (0.50) EPHA2RAMP3CALCRPLK1GRB2
SCHEMBL31031563 0.88 RAMP3 (0.49) EPHA2RAMP3CALCRGRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3187508-B1 LYSOSOMAL TARGETING PEPTIDES AND USES THEREOF BIOMARIN PHARM INC (US) 2026-04-22 — — EP disclosed
US-20230241187-A1 Lysosomal Targeting Peptides and Uses Thereof BIOMARIN PHARMACEUTICAL INC. 2023-08-03 — — US disclosed
US-20220354934-A1 Lysosomal Targeting Peptides and Uses Thereof BIOMARIN PHARMACEUTICAL INC. 2022-11-10 — — US disclosed
US-11351231-B2 Lysosomal targeting peptides and uses thereof BIOMARIN PHARMACEUTICAL INC. (US) 2022-06-07 — — US disclosed