Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL360496 | 1.00 | CA1 (0.57) | CA1CA2CA12CA4CA7 | |
| Hydrochloric Acid SCHEMBL30993972 | 0.98 | CA12 (0.55) | CA1CA2CA12CA4CA7 | |
| SCHEMBL6867123 | 0.82 | ALDH1A1 (0.51) | CA1CA2CA12CA4CA7 | |
| SCHEMBL3191755 | 0.82 | MAPT (0.69) | CA1CA2CA12CA4CA7 | |
| SCHEMBL6240378 | 0.82 | APP (0.48) | CA1CA2CA12CA4CA7 | |
| SCHEMBL1639354 | 0.82 | CA1 (0.60) | CA1CA2CA12CA4CA7 | |
| SCHEMBL24271124 | 0.81 | CA1 (0.52) | CA1CA2CA12CA4CA7 | |
| SCHEMBL11765492 | 0.80 | MAPT (0.55) | ALDH1A1MAPTGAARAB9AL3MBTL1 | |
| SCHEMBL5923798 | 0.80 | MAPT (0.67) | CA1CA2CA12CA4CA7 | |
| SCHEMBL7715781 | 0.79 | APP (0.44) | CA1CA2CA12CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036001-B | Benzo [ b ] thiophene compounds as STING agonists | 默沙东公司 | 2022-03-22 | — | — | CN | disclosed |