SCHEMBL360496

SCHEMBL360496

CNc1ccccc1OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA12 O43570 1/20 0.57
CA4 P22748 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
ALDH1A1 P00352 5/20 0.55
MAPT P10636 3/20 0.55
NPC1 O15118 1/20 0.55
GAA P10253 1/20 0.55
RAB9A P51151 1/20 0.55
MAPK1 P28482 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
HPGD P15428 2/20 0.50
HTT P42858 1/20 0.50
APP P05067 3/20 0.48
KDM4E B2RXH2 2/20 0.48
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29636384 1.00 CA1 (0.57) CA1CA2CA12CA4CA7
Hydrochloric Acid SCHEMBL30993972 0.98 CA12 (0.55) CA1CA2CA12CA4CA7
SCHEMBL6867123 0.82 ALDH1A1 (0.51) CA1CA2CA12CA4CA7
SCHEMBL3191755 0.82 MAPT (0.69) CA1CA2CA12CA4CA7
SCHEMBL6240378 0.82 APP (0.48) CA1CA2CA12CA4CA7
SCHEMBL1639354 0.82 CA1 (0.60) CA1CA2CA12CA4CA7
SCHEMBL24271124 0.81 CA1 (0.52) CA1CA2CA12CA4CA7
SCHEMBL11765492 0.80 MAPT (0.55) ALDH1A1MAPTGAARAB9AL3MBTL1
SCHEMBL5923798 0.80 MAPT (0.67) CA1CA2CA12CA4CA7
SCHEMBL7715781 0.79 APP (0.44) CA1CA2CA12CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 801 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
EP-2593425-B1 THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHOD OF USE AGIOS PHARMACEUTICALS INC (US) 2018-10-17 EP claimed
CN-107105667-A Probe for being imaged Huntington protein CHDI基金会股份有限公司 2017-08-29 CN claimed
US-20160264621-A1 THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE AGIOS PHARMACEUTICALS, INC (US) 2016-09-15 US claimed
US-20130184222-A1 THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE AGIOS PHARMACEUTICALS, INC (US) 2013-07-18 US claimed
EP-2593425-A1 THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHOD OF USE Agios Pharmaceuticals, Inc. (US) 2013-05-22 EP claimed
WO-2012009678-A1 THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHOD OF USE AGIOS PHARMACEUTICALS, INC. (US) 2012-01-19 WO claimed
EP-2079699-A1 QUINOLINE DERIVATIVES Envivo Pharmaceuticals, Inc. (US) 2009-07-22 EP claimed
WO-2008014602-A1 QUINOLINE DERIVATIVES ENVIVO PHARMACEUTICALS, INC. (US) 2008-02-07 WO claimed
EP-1884513-A1 PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME Japan Tobacco, Inc. (JP) 2008-02-06 EP claimed
US-20070032529-A1 Pyrazole compounds and their use as antidiabetes agents JAPAN TOBACCO INC. (JP) 2007-02-08 US claimed
US-6984673-B2 Dental cement composition KURARAY CO., LTD. (JP) 2006-01-10 US claimed
EP-0717739-B1 1,4-Benzodioxane derivatives having affinity for D2 receptors and utility in the treatment of psychoses KNOLL AG (DE) 2000-03-29 EP claimed
CN-122074072-A Novel and cost-effective polycondensation of 2-methoxymethyl-p-phenylenediamine 威娜德国有限责任公司 2026-05-22 CN disclosed
CN-120987794-B N-p-hydroxyphenyl-N-methyl-2-acetyl acrylamide compound, and preparation method and application thereof 中国农业大学 2026-05-15 CN disclosed
US-20260097139-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GnRHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-04-09 US disclosed
US-4060544-A COUPLERS GAF CORPORATION (US) 1977-11-29 US disclosed
US-4039524-A Keto-amido containing phenylazo benzothiazole dyestuffs GAF CORPORATION (US) 1977-08-02 US disclosed
US-4021471-A Formamidines useful as ultraviolet light absorbers GIVAUDAN CORPORATION (US) 1977-05-03 US disclosed
US-3931145-A POLYESTER GAF CORPORATION (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097139-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GnRHR) TARGETED THERAPEUTICS AND USES THEREOF GNRHR, GHRHR, FSHR CA1 1710/4885CA2 468/4885CA12 375/4885
US-20130184222-A1 THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE IDH1, IDH3B, IDH3A CA1 1632/4885CA2 1914/4885CA12 1118/4885
US-20070032529-A1 Pyrazole compounds and their use as antidiabetes agents PYGL, GYS2, AGL CA1 1635/4885CA2 551/4885CA12 2116/4885
US-20160264621-A1 THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHODS OF USE IDH1, IDH3B, IDH3A CA1 1632/4885CA2 1914/4885CA12 1118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.