Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20022281 | 1.00 | STING1 (0.67) | STING1KDM4EMAPTPOLBCCNC | |
| SCHEMBL7433969 | 0.90 | STING1 (0.72) | STING1KDM4EPOLBCCNCCDK8 | |
| SCHEMBL20049321 | 0.87 | STING1 (0.68) | STING1KDM4EPOLBCCNCCDK8 | |
| SCHEMBL26931568 | 0.86 | STING1 (0.50) | STING1KDM4EMAPTCCNCCDK8 | |
| SCHEMBL30682880 | 0.86 | STING1 (0.50) | STING1KDM4EMAPTCCNCCDK8 | |
| SCHEMBL29636411 | 0.86 | STING1 (0.67) | STING1KDM4EPOLBCCNCCDK8 | |
| SCHEMBL20022282 | 0.86 | STING1 (0.67) | STING1KDM4EPOLBCCNCCDK8 | |
| SCHEMBL20026433 | 0.84 | STING1 (0.62) | STING1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL24175593 | 0.84 | CCNC (0.49) | STING1KDM4EMAPTPOLBCCNC | |
| SCHEMBL26931877 | 0.83 | STING1 (0.75) | STING1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536672-A1 | STING AGONIST COMPOUNDS | Sutro Biopharma, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| CN-119654330-A | STING agonist compounds | 苏特罗生物制药公司 | 2025-03-18 | — | — | CN | disclosed |
| WO-2023239675-A1 | STING AGONIST COMPOUNDS | SUTRO BIOPHARMA, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| CN-110036001-B | Benzo [ b ] thiophene compounds as STING agonists | 默沙东公司 | 2022-03-22 | — | — | CN | disclosed |