Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.46 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1643613 | 1.00 | LMNA (0.46) | LMNAMAPTMEN1KMT2APLIN1 | |
| SCHEMBL29362469 | 1.00 | LMNA (0.46) | LMNAMAPTMEN1KMT2APLIN1 | |
| SCHEMBL1644169 | 0.82 | KMT2A (0.51) | LMNAMAPTMEN1KMT2APLIN1 | |
| SCHEMBL29665865 | 0.82 | KMT2A (0.51) | LMNAMAPTMEN1KMT2APLIN1 | |
| SCHEMBL28701340 | 0.82 | KAT6A (0.47) | LMNAPOLBGAAKAT6ACTSD | |
| SCHEMBL28295204 | 0.82 | KAT6A (0.47) | LMNAPOLBGAAKAT6ACTSD | |
| SCHEMBL27585725 | 0.79 | TSHR (0.58) | LMNAMAPTMEN1KMT2APLIN1 | |
| SCHEMBL28927886 | 0.78 | KMT2A (0.51) | LMNAMAPTMEN1KMT2APLIN1 | |
| SCHEMBL28766154 | 0.78 | KMT2A (0.51) | LMNAMAPTMEN1KMT2APLIN1 | |
| SCHEMBL1642002 | 0.77 | CYP19A1 (0.41) | LMNAMAPTMEN1KMT2APLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734616-B | Method for synthesizing (Z) -3-amino-2- (2-fluoro-3-methoxyphenyl) -2-ethyl crotonate by two-step method | 安徽诺全药业有限公司 | 2022-05-13 | — | — | CN | disclosed |