SCHEMBL29636735

SCHEMBL29636735

O=c1cc(-c2ccc(O)cc2)oc2ccc(O)c(O)c12

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.78
KMT2A Q03164 6/20 0.75
GABRP O00591 4/20 0.75
GABRD O14764 4/20 0.75
GABRA1 P14867 4/20 0.75
GABRB1 P18505 4/20 0.75
GABRG2 P18507 4/20 0.75
GABRB3 P28472 4/20 0.75
GABRA5 P31644 4/20 0.75
GABRA3 P34903 4/20 0.75
GABRA2 P47869 4/20 0.75
GABRB2 P47870 4/20 0.75
GABRA4 P48169 4/20 0.75
GABRE P78334 4/20 0.75
GABRA6 Q16445 4/20 0.75
GABRG1 Q8N1C3 4/20 0.75
GABRG3 Q99928 4/20 0.75
GABRQ Q9UN88 4/20 0.75
PKM P14618 3/20 0.75
CYP1A1 P04798 3/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5084165 0.87 ABCB1 (0.75) LCKKMT2AGABRPGABRDGABRA1
Scutellarein SCHEMBL29004586 0.86 KMT2A (1.00) LCKKMT2AGABRPGABRDGABRA1
Scutellarein SCHEMBL142093 0.86 KMT2A (1.00) LCKKMT2AGABRPGABRDGABRA1
Scutellarein SCHEMBL29692708 0.86 KMT2A (1.00) LCKKMT2AGABRPGABRDGABRA1
SCHEMBL24088771 0.84 CBS (0.82) LCKKMT2AGABRPGABRDGABRA1
Scutellarein SCHEMBL15090395 0.84 KMT2A (0.97) LCKKMT2AGABRPGABRDGABRA1
Scutellarein SCHEMBL28016997 0.84 KMT2A (0.97) LCKKMT2AGABRPGABRDGABRA1
Scutellarein SCHEMBL1900314 0.84 KMT2A (0.97) LCKKMT2AGABRPGABRDGABRA1
SCHEMBL30442786 0.84 CBS (0.82) LCKKMT2AGABRPGABRDGABRA1
Scutellarein SCHEMBL28230300 0.84 KMT2A (0.97) LCKKMT2AGABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240299464-A1 BOTANICAL COMPOUNDS, METHODS, AND PROCEDURES FOR MEDICINAL TREATMENT RELATED TO IMMUNOINFLAMMATION, NEUROINFLAMMATION, DEPRESSION, MEMORY, FOCUS, AND NERVE DEGENERATION NGUYEN MINH H (US) 2024-09-12 US disclosed
CN-118255836-A Preparation method of scutellarin modified polypeptide 深圳市维琪科技股份有限公司 2024-06-28 CN disclosed
CN-116725970-A Breviscapine tablet and preparation process thereof 广东彼迪药业有限公司 2023-09-12 CN disclosed
CN-114470061-A New extraction process of 'Dingyinnaotong' pharmaceutical composition and new applicable crowd thereof 昆药集团股份有限公司 2022-05-13 CN disclosed