Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1A1 | Q02108 | 18/20 | 0.43 |
| ▸ | GUCY1B1 | Q02153 | 18/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23161960 | 1.00 | GUCY1A1 (0.43) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL255832 | 0.86 | ADORA3 (0.57) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL458874 | 0.84 | ADORA3 (0.57) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL23162011 | 0.84 | ADORA3 (0.43) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL12298795 | 0.84 | PDE5A (0.50) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL23161921 | 0.83 | ADORA3 (0.48) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL24555990 | 0.82 | ADORA3 (0.42) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL23161978 | 0.80 | ADORA3 (0.42) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL29637211 | 0.80 | ADORA3 (0.42) | GUCY1A1GUCY1B1ADORA3KCNH2 | |
| SCHEMBL23161966 | 0.78 | ADORA3 (0.51) | GUCY1A1GUCY1B1ADORA3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609883-B1 | FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2022-06-29 | — | — | EP | disclosed |