Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | GUCY1A1 | Q02108 | 9/20 | 0.52 |
| ▸ | GUCY1B1 | Q02153 | 9/20 | 0.52 |
| ▸ | PDE5A | O76074 | 9/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255832 | 0.96 | ADORA3 (0.57) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL6642458 | 0.85 | PDE5A (0.54) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL23161960 | 0.84 | GUCY1A1 (0.43) | ADORA3KCNH2GUCY1A1GUCY1B1 | |
| SCHEMBL29637216 | 0.84 | GUCY1A1 (0.43) | ADORA3KCNH2GUCY1A1GUCY1B1 | |
| SCHEMBL29382996 | 0.84 | ADORA3 (0.60) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL417331 | 0.84 | ADORA3 (0.60) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL10252555 | 0.84 | ADORA3 (0.62) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL174847 | 0.83 | ADORA3 (0.67) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL175455 | 0.83 | ADORA3 (0.57) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL10064749 | 0.83 | ADORA3 (0.57) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010577-A1 | SUBSTITUTED OXAZOLIDINONES AND OXAZINANONES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010577-A1 | SUBSTITUTED OXAZOLIDINONES AND OXAZINANONES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-26 | — | — | WO | disclosed |