Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 5/20 | 0.46 |
| ▸ | BUB1 | O43683 | 2/20 | 0.46 |
| ▸ | GUCY1A1 | Q02108 | 9/20 | 0.45 |
| ▸ | GUCY1B1 | Q02153 | 9/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23161994 | 1.00 | ADORA3 (0.52) | ADORA3KCNH2KDM4ETP53RAB9A | |
| SCHEMBL23162013 | 0.90 | BUB1 (0.48) | ADORA3KCNH2KDM4EPDE5ABUB1 | |
| SCHEMBL29637215 | 0.90 | BUB1 (0.48) | ADORA3KCNH2KDM4EPDE5ABUB1 | |
| SCHEMBL29637224 | 0.89 | PDE5A (0.46) | ADORA3KCNH2PDE5ABUB1GUCY1A1 | |
| SCHEMBL23161961 | 0.89 | PDE5A (0.46) | ADORA3KCNH2PDE5ABUB1GUCY1A1 | |
| SCHEMBL23162030 | 0.87 | BUB1 (0.54) | ADORA3KCNH2TP53RAB9AHSD17B10 | |
| SCHEMBL29637223 | 0.87 | BUB1 (0.54) | ADORA3KCNH2TP53RAB9AHSD17B10 | |
| SCHEMBL23161966 | 0.87 | ADORA3 (0.51) | ADORA3KCNH2PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL29637237 | 0.87 | ADORA3 (0.51) | ADORA3KCNH2PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL23161909 | 0.83 | BUB1 (0.51) | ADORA3KCNH2TP53PDE5ABUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609883-B1 | FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2022-06-29 | — | — | EP | disclosed |