Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | GUCY1A1 | Q02108 | 17/20 | 0.47 |
| ▸ | GUCY1B1 | Q02153 | 17/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23161966 | 1.00 | ADORA3 (0.51) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL23161921 | 0.88 | ADORA3 (0.48) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL23161988 | 0.87 | GUCY1A1 (0.51) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL23161994 | 0.87 | ADORA3 (0.52) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL29637225 | 0.87 | ADORA3 (0.52) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL23161945 | 0.86 | ADORA3 (0.51) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL23161959 | 0.85 | ADORA3 (0.50) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL30937506 | 0.85 | ADORA3 (0.50) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL23161926 | 0.85 | BUB1 (0.51) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A | |
| SCHEMBL29637235 | 0.85 | BUB1 (0.51) | ADORA3KCNH2GUCY1A1GUCY1B1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609883-B1 | FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2022-06-29 | — | — | EP | disclosed |