Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.41 |
| ▸ | KDM6B | O15054 | 2/20 | 0.41 |
| ▸ | KDM5C | P41229 | 2/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.30 |
| ▸ | GABRD | O14764 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29637409 | 0.89 | TSHR (0.48) | LMNATSHRVCAM1CYP1A2MAPK1 | |
| SCHEMBL6441150 | 0.78 | EGLN1 (0.42) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL14661595 | 0.77 | EGLN1 (0.45) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL15270647 | 0.76 | LMNA (0.45) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL13010227 | 0.74 | EGLN1 (0.39) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL18056180 | 0.74 | EGLN1 (0.39) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL4335657 | 0.73 | LMNA (0.32) | LMNATSHR | |
| SCHEMBL7439619 | 0.72 | LMNA (0.41) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL10476496 | 0.72 | EGLN1 (0.37) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL18056178 | 0.72 | EGLN1 (0.37) | EGLN1KDM6BKDM5CPHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119033775-A | 2-Arylbenzimidazoles as PPARGC1A activators for the treatment of neurodegenerative diseases | 小利兰·斯坦福大学董事会 | 2024-11-29 | — | — | CN | disclosed |
| CN-114423740-A | Pyrazole derivatives for controlling arthropods | 拜耳动物保健有限责任公司 | 2022-04-29 | — | — | CN | disclosed |