Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29637404 | 0.89 | EGLN1 (0.41) | TSHRLMNACYP1A2VCAM1MAPK1 | |
| SCHEMBL6442341 | 0.79 | TSHR (0.50) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL29226761 | 0.76 | TSHR (0.50) | TSHRSLC22A6LMNAAKR1B1ALDH1A1 | |
| SCHEMBL10553643 | 0.75 | TSHR (0.54) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL18620 | 0.74 | LMNA (0.61) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL15270814 | 0.74 | LMNA (0.50) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL10009910 | 0.74 | TSHR (0.44) | TSHRSLC22A6LMNANFKB1AKR1B1 | |
| SCHEMBL15271163 | 0.72 | TSHR (0.52) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL11752180 | 0.72 | TSHR (0.52) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL15270662 | 0.72 | TSHR (0.52) | TSHRSLC22A6LMNANFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423740-A | Pyrazole derivatives for controlling arthropods | 拜耳动物保健有限责任公司 | 2022-04-29 | — | — | CN | disclosed |