SCHEMBL29637487

SCHEMBL29637487

Cn1nc(C(F)(F)F)cc1OC(F)F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 3/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
PTGS1 P23219 2/20 0.40
PTGS2 P35354 2/20 0.40
ALOX5 P09917 1/20 0.40
TGFBR1 P36897 1/20 0.38
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.35
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC10 Q969S8 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12924480 0.86 KMT2A (0.47) KMT2AALDH1A1ADORA2AADORA1PTGS1
SCHEMBL29735853 0.83 KMT2A (0.36) KMT2AALDH1A1ADORA2AADORA1PTGS1
SCHEMBL5382190 0.81 TGFBR1 (0.39) KMT2AALDH1A1ADORA2AADORA1PTGS1
SCHEMBL13490122 0.79 KMT2A (0.54) KMT2AALDH1A1ADORA2AADORA1PTGS1
SCHEMBL30363332 0.78 KMT2A (0.50) KMT2AALDH1A1ADORA2AADORA1PTGS1
SCHEMBL8117794 0.78 KMT2A (0.49) KMT2AALDH1A1ADORA2AADORA1PTGS1
SCHEMBL13404489 0.78 KMT2A (0.49) KMT2AALDH1A1ADORA2AADORA1PTGS1
SCHEMBL8932302 0.77 KMT2A (0.44) KMT2AALDH1A1ADORA2AADORA1PTGS1
SCHEMBL17321550 0.76 KCNH2 (0.37) KMT2ALMNA
SCHEMBL5198293 0.75 KMT2A (0.54) KMT2AALDH1A1ADORA2AADORA1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661438-A Synthesis method of 1-methyl-3-trifluoromethyl-4-chloromethyl-5-difluoromethoxy-1-H-pyrazole 苏利(宁夏)新材料科技有限公司 2025-03-21 CN claimed
CN-119490457-A Method for continuously synthesizing intermediate of pyrazoxyfop 苏利(宁夏)新材料科技有限公司 2025-02-21 CN claimed
WO-2024209278-A1 A PROCESS FOR THE PREPARATION OF PYROXASULFONE GHARDA CHEMICALS LIMITED (IN) 2024-10-10 WO claimed
CN-118221663-A Continuous synthesis method of pyribenzoxim 吉林凯莱英医药化学有限公司 2024-06-21 CN claimed
CN-120698932-A Pyricularia sulfone Process for the preparation of intermediates 苏利(宁夏)新材料科技有限公司 2025-09-26 CN disclosed
CN-119954720-A Preparation method of 1-methyl-3- (trifluoromethyl) -4- (chloromethyl) -5- (difluoromethoxy) -1H-pyrazole 利尔化学股份有限公司 2025-05-09 CN disclosed
CN-119192093-B Pyricularia sulfone Process for the preparation of intermediates 衢州凯沃化工有限公司 2025-04-18 CN disclosed
CN-119678941-A Weeding composition compounded by fenpyrad and topramezone and application thereof 青岛瀚生生物科技股份有限公司 2025-03-25 CN disclosed
CN-119661438-A Synthesis method of 1-methyl-3-trifluoromethyl-4-chloromethyl-5-difluoromethoxy-1-H-pyrazole 苏利(宁夏)新材料科技有限公司 2025-03-21 CN disclosed
EP-4519257-A1 PROCESS FOR THE PREPARATION OF PYROXASULFONE Adama Agan Ltd. (IL) 2025-03-12 EP disclosed
CN-119490457-A Method for continuously synthesizing intermediate of pyrazoxyfop 苏利(宁夏)新材料科技有限公司 2025-02-21 CN disclosed
CN-119490457-A Method for continuously synthesizing intermediate of pyrazoxyfop 苏利(宁夏)新材料科技有限公司 2025-02-21 CN disclosed
CN-119318925-A Continuous production system and continuous production method of 5- (difluoromethoxy) -4-chloromethyl-1-methyl-3- (trifluoromethyl) -1H-pyrazole 天津凯莱英医药科技发展有限公司 2025-01-17 CN disclosed
CN-119234818-A Sulfopyrazoles and fluorine-containing compounds Mixed herbicide of metazachlor 南京华洲药业有限公司 2025-01-03 CN disclosed
CN-119192093-A Pyricularia sulfone Process for the preparation of intermediates 衢州凯沃化工有限公司 2024-12-27 CN disclosed
WO-2024261759-A1 PROCESS FOR THE PREPARATION OF PYROXASULFONE ADAMA AGAN LTD. (IL) 2024-12-26 WO disclosed
WO-2024209278-A1 A PROCESS FOR THE PREPARATION OF PYROXASULFONE GHARDA CHEMICALS LIMITED (IN) 2024-10-10 WO disclosed
CN-114946870-B Penoxsulam and metazophos dispersible oil suspending agent and preparation method and application thereof 浙江天丰生物科学有限公司 2024-02-02 CN disclosed
CN-114946870-A Penoxsulam and pyraflufen-ethyl dispersible oil suspending agent as well as preparation method and application thereof 浙江天丰生物科学有限公司 2022-08-30 CN disclosed
CN-114208837-A Weeding composition and application thereof 青岛瀚生生物科技股份有限公司 2022-03-22 CN disclosed