Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753817 | 0.86 | ALDH1A1 (0.54) | KMT2AALDH1A1ADORA2AADORA1TGFBR1 | |
| SCHEMBL20457202 | 0.86 | KMT2A (0.54) | KMT2AALDH1A1ADORA2AADORA1TGFBR1 | |
| SCHEMBL26750160 | 0.83 | KMT2A (0.51) | KMT2AALDH1A1ADORA2AADORA1TGFBR1 | |
| SCHEMBL4737609 | 0.81 | KMT2A (0.50) | KMT2AALDH1A1ADORA2AADORA1TGFBR1 | |
| SCHEMBL30363332 | 0.81 | KMT2A (0.50) | KMT2AALDH1A1ADORA2AADORA1TGFBR1 | |
| SCHEMBL4977409 | 0.80 | KMT2A (0.49) | KMT2AALDH1A1ADORA2AADORA1TGFBR1 | |
| SCHEMBL4166964 | 0.80 | ALDH1A1 (0.56) | KMT2AALDH1A1ADORA2AADORA1TGFBR1 | |
| SCHEMBL13490122 | 0.79 | KMT2A (0.54) | KMT2AALDH1A1ADORA2AADORA1TGFBR1 | |
| SCHEMBL24305797 | 0.79 | KMT2A (0.48) | KMT2AALDH1A1ADORA2AADORA1TGFBR1 | |
| SCHEMBL20797272 | 0.79 | ALDH1A1 (0.65) | KMT2AALDH1A1ADORA2AADORA1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799657-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | Syngenta Limited (GB) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006037945-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |