Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 5/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055655 | 1.00 | CDK5 (0.42) | CDK5CDK5R1NOS3NOS1NOS2 | |
| SCHEMBL601423 | 0.96 | NOS3 (0.47) | CDK5CDK5R1NOS3NOS1NOS2 | |
| SCHEMBL929921 | 0.94 | NOS3 (0.45) | CDK5CDK5R1NOS3NOS1NOS2 | |
| SCHEMBL4115818 | 0.94 | NOS3 (0.45) | CDK5CDK5R1NOS3NOS1NOS2 | |
| SCHEMBL27584738 | 0.74 | CDK5 (0.42) | CDK5CDK5R1NOS3NOS1NOS2 | |
| SCHEMBL11561562 | 0.74 | CDK5 (0.47) | CDK5CDK5R1NOS3NOS1NOS2 | |
| SCHEMBL29508228 | 0.74 | CDK5 (0.47) | CDK5CDK5R1NOS3NOS1NOS2 | |
| SCHEMBL1819834 | 0.74 | GRM5 (0.47) | CDK5CDK5R1NOS3NOS1NOS2 | |
| SCHEMBL17781242 | 0.72 | ALDH1A1 (0.37) | KDM4EALDH1A1POLBHSP90AA1CCNA2 | |
| SCHEMBL23092083 | 0.72 | ALDH1A1 (0.38) | KDM4EALDH1A1POLBHSP90AA1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423758-B | Antibacterial compounds | 爱尔兰詹森科学公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-117440958-A | Antibacterial compounds | 爱尔兰詹森科学公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-117396475-A | Antibacterial compounds | 爱尔兰詹森科学公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-114423758-A | Antibacterial compounds | 爱尔兰詹森科学公司 | 2022-04-29 | — | — | CN | disclosed |