Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.67 |
| ▸ | CTSS | P25774 | 3/20 | 0.67 |
| ▸ | CTSK | P43235 | 3/20 | 0.67 |
| ▸ | CTSH | P09668 | 1/20 | 0.67 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.58 |
| ▸ | NMBR | P28336 | 2/20 | 0.57 |
| ▸ | GRPR | P30550 | 2/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | NPY4R | P50391 | 1/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.55 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.54 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.54 |
| ▸ | GLP1R | P43220 | 4/20 | 0.54 |
| ▸ | GCGR | P47871 | 4/20 | 0.54 |
| ▸ | GIPR | P48546 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638083 | 0.98 | CTSL (0.67) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL31725194 | 0.91 | CTSL (0.63) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL30631666 | 0.91 | CTSL (0.62) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL31182510 | 0.88 | C5AR1 (0.65) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL30091430 | 0.87 | CTSL (0.67) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL31475687 | 0.87 | CTSL (0.66) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL31307939 | 0.87 | CXCR4 (0.65) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL30262205 | 0.87 | CTSL (0.65) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL31475675 | 0.86 | CTSL (0.60) | CTSLCTSSCTSKCTSHCXCR4 | |
| SCHEMBL31194149 | 0.86 | KISS1R (0.62) | CTSLCTSSCTSKCTSHCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4591934-A2 | VARIANTS OF C-TYPE NATRIURETIC PEPTIDE | BioMarin Pharmaceutical Inc. (US) | 2025-07-30 | — | — | EP | disclosed |
| EP-4523749-A2 | VARIANTS OF C-TYPE NATRIURETIC PEPTIDE | BioMarin Pharmaceutical Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| EP-4029512-A1 | VARIANTS OF C-TYPE NATRIURETIC PEPTIDE | BioMarin Pharmaceutical Inc. (US) | 2022-07-20 | — | — | EP | disclosed |
| EP-4019038-A2 | USE OF C-TYPE NATRIURETIC PEPTIDE VARIANTS TO TREAT OSTEOARTHRITIS | BioMarin Pharmaceutical Inc. (US) | 2022-06-29 | — | — | EP | disclosed |