Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 12/20 | 0.39 |
| ▸ | TYK2 | P29597 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 7/20 | 0.36 |
| ▸ | SRC | P12931 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557315 | 1.00 | BTK (0.39) | BTKTYK2POLBGAALYN | |
| SCHEMBL29638361 | 0.90 | TYK2 (0.38) | BTKTYK2POLBGAALYN | |
| SCHEMBL29638379 | 0.88 | TYK2 (0.41) | BTKTYK2POLBGAALYN | |
| SCHEMBL29638454 | 0.88 | TYK2 (0.41) | BTKTYK2POLBGAALYN | |
| SCHEMBL24557268 | 0.85 | TYK2 (0.49) | TYK2POLBGAA | |
| SCHEMBL29638481 | 0.85 | TYK2 (0.49) | TYK2POLBGAA | |
| SCHEMBL24557258 | 0.85 | NPC1 (0.41) | BTKTYK2POLBGAALYN | |
| SCHEMBL29638464 | 0.85 | NPC1 (0.41) | BTKTYK2POLBGAALYN | |
| SCHEMBL24557255 | 0.84 | TYK2 (0.42) | BTKTYK2POLBGAALYN | |
| SCHEMBL29638444 | 0.84 | TYK2 (0.38) | BTKTYK2POLBGAALYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |