Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.46 |
| ▸ | SRC | P12931 | 12/20 | 0.46 |
| ▸ | LYN | P07948 | 9/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557274 | 1.00 | BTK (0.46) | BTKSRCLYNABL1JAK1 | |
| SCHEMBL29638394 | 0.83 | TYK2 (0.40) | BTKSRCLYNABL1JAK1 | |
| SCHEMBL27199231 | 0.83 | TYK2 (0.40) | BTKSRCLYNABL1JAK1 | |
| SCHEMBL29638480 | 0.82 | BTK (0.45) | BTKSRCLYNJAK1TYK2 | |
| SCHEMBL24557294 | 0.82 | BTK (0.41) | BTKSRCLYNJAK1TYK2 | |
| SCHEMBL24557272 | 0.82 | BTK (0.45) | BTKSRCLYNJAK1TYK2 | |
| SCHEMBL29638402 | 0.82 | BTK (0.41) | BTKSRCLYNJAK1TYK2 | |
| SCHEMBL24557265 | 0.81 | JAK1 (0.43) | BTKSRCLYNJAK1TYK2 | |
| SCHEMBL29638331 | 0.81 | JAK1 (0.43) | BTKSRCLYNJAK1TYK2 | |
| SCHEMBL24557309 | 0.81 | JAK1 (0.46) | BTKSRCLYNJAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |