SCHEMBL29638394 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	TYK2	P29597	12/20	0.40

▸	JAK1	P23458	2/20	0.39

▸	TP53	P04637	1/20	0.35

▸	LYN	P07948	3/20	0.35

▸	SRC	P12931	3/20	0.35

▸	BTK	Q06187	3/20	0.35

▸	ALOX5	P09917	1/20	0.34

▸	ABL1	P00519	1/20	0.33

▸	WEE1	P30291	2/20	0.33

▸	JAK2	O60674	1/20	0.33

▸	JAK3	P52333	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL27199231	1.00	TYK2 (0.40)	TYK2JAK1TP53LYNSRC
SCHEMBL29638330	0.84	GAA (0.45)	TYK2LYNSRCBTKABL1
SCHEMBL29638404	0.83	TYK2 (0.40)	TYK2JAK1TP53
SCHEMBL24557274	0.83	BTK (0.46)	TYK2JAK1LYNSRCBTK
SCHEMBL24557308	0.83	TYK2 (0.40)	TYK2JAK1TP53
SCHEMBL24557292	0.83	TYK2 (0.36)	TYK2JAK1LYNSRCBTK
SCHEMBL29638409	0.83	BTK (0.46)	TYK2JAK1LYNSRCBTK
SCHEMBL29638445	0.83	TYK2 (0.36)	TYK2JAK1LYNSRCBTK
SCHEMBL24557258	0.81	NPC1 (0.41)	TYK2TP53LYNSRCBTK
SCHEMBL29638464	0.81	NPC1 (0.41)	TYK2TP53LYNSRCBTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022136914-A1	TYK2 INHIBITORS AND USES THEREOF	SUDO BIOSCIENCES LIMITED (GB)	2022-06-30	—	—	WO	disclosed