SCHEMBL29638417 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	BTK	Q06187	10/20	0.40

▸	SRC	P12931	7/20	0.39

▸	LYN	P07948	6/20	0.39

▸	HPGD	P15428	1/20	0.38

▸	PIK3CA	P42336	1/20	0.38

▸	PRKDC	P78527	1/20	0.38

▸	SLC22A12	Q96S37	2/20	0.37

▸	MIF	P14174	1/20	0.36

▸	TYK2	P29597	1/20	0.35

▸	CDK4	P11802	1/20	0.35

▸	CDK6	Q00534	1/20	0.35

▸	PGR	P06401	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24557248	1.00	BTK (0.40)	BTKSRCLYNHPGDPIK3CA
SCHEMBL29638318	0.85	BTK (0.53)	BTKSRCLYNHPGDTYK2
SCHEMBL29638463	0.85	AR (0.47)	BTKLYNSLC22A12
SCHEMBL24557291	0.85	AR (0.47)	BTKLYNSLC22A12
SCHEMBL29638483	0.84	BTK (0.40)	BTKSRCLYNHPGDCDK4
SCHEMBL24557323	0.83	AR (0.49)	SLC22A12
SCHEMBL29638343	0.83	AR (0.49)	SLC22A12
SCHEMBL29638427	0.83	SLC22A12 (0.45)	SLC22A12TYK2
SCHEMBL24557301	0.82	BTK (0.45)	BTKSRCLYN
SCHEMBL29638446	0.82	BTK (0.45)	BTKSRCLYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022136914-A1	TYK2 INHIBITORS AND USES THEREOF	SUDO BIOSCIENCES LIMITED (GB)	2022-06-30	—	—	WO	disclosed