Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 14/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557291 | 1.00 | AR (0.47) | ARSLC22A12CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL24557295 | 0.88 | BTK (0.43) | BTKLYN | |
| SCHEMBL29638577 | 0.88 | BTK (0.43) | BTKLYN | |
| SCHEMBL29638343 | 0.87 | AR (0.49) | ARSLC22A12 | |
| SCHEMBL24557323 | 0.87 | AR (0.49) | ARSLC22A12 | |
| SCHEMBL29638427 | 0.86 | SLC22A12 (0.45) | SLC22A12 | |
| SCHEMBL24557248 | 0.85 | BTK (0.40) | SLC22A12BTKLYN | |
| SCHEMBL29638417 | 0.85 | BTK (0.40) | SLC22A12BTKLYN | |
| SCHEMBL24557301 | 0.82 | BTK (0.45) | BTKLYN | |
| SCHEMBL29638446 | 0.82 | BTK (0.45) | BTKLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |