Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 19/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638448 | 0.88 | JAK1 (0.41) | JAK1TYK2 | |
| SCHEMBL29638463 | 0.86 | AR (0.47) | SLC22A12 | |
| SCHEMBL24557291 | 0.86 | AR (0.47) | SLC22A12 | |
| SCHEMBL29638467 | 0.86 | BTK (0.41) | SLC22A12JAK1TYK2 | |
| SCHEMBL27199225 | 0.86 | BTK (0.41) | SLC22A12JAK1TYK2 | |
| SCHEMBL24557323 | 0.84 | AR (0.49) | SLC22A12 | |
| SCHEMBL29638343 | 0.84 | AR (0.49) | SLC22A12 | |
| SCHEMBL29638471 | 0.84 | IDH1 (0.34) | JAK1TYK2 | |
| SCHEMBL24557248 | 0.83 | BTK (0.40) | SLC22A12TYK2 | |
| SCHEMBL29638417 | 0.83 | BTK (0.40) | SLC22A12TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |