Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.41 |
| ▸ | SRC | P12931 | 11/20 | 0.41 |
| ▸ | LYN | P07948 | 9/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638335 | 0.84 | TYK2 (0.34) | BTKMAT2AMAPK1 | |
| SCHEMBL29638577 | 0.79 | BTK (0.43) | BTKSRCLYNMAPK1 | |
| SCHEMBL24557295 | 0.79 | BTK (0.43) | BTKSRCLYNMAPK1 | |
| SCHEMBL29638458 | 0.79 | MAPT (0.38) | MAT2AMAPK1 | |
| SCHEMBL29638492 | 0.79 | BTK (0.48) | BTKSRCLYN | |
| SCHEMBL29638318 | 0.78 | BTK (0.53) | BTKSRCLYN | |
| SCHEMBL29638448 | 0.78 | JAK1 (0.41) | BTKSRCLYN | |
| SCHEMBL29638446 | 0.78 | BTK (0.45) | BTKSRCLYN | |
| SCHEMBL24557301 | 0.78 | BTK (0.45) | BTKSRCLYN | |
| SCHEMBL24557257 | 0.77 | PTGS2 (0.42) | BTKSRCLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |