Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | MAT2A | P31153 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638429 | 0.79 | BTK (0.41) | MAPK1MAT2A | |
| SCHEMBL29638335 | 0.78 | TYK2 (0.34) | MAPTKDM4ENSD2ALDH1A1MAPK1 | |
| SCHEMBL29638327 | 0.72 | CCNA2 (0.40) | MAPTHPGDCYP1A2CYP2C19 | |
| SCHEMBL29638428 | 0.71 | CYP1A2 (0.44) | MAPTHPGDMEN1CYP1A2CYP2C19 | |
| SCHEMBL19493638 | 0.70 | KDM4E (0.37) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL21604599 | 0.68 | KDM4E (0.46) | MAPTKDM4ENSD2ALDH1A1MEN1 | |
| SCHEMBL29638432 | 0.66 | HPGD (0.41) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL22323295 | 0.65 | KDM4E (0.42) | MAPTKDM4ENSD2ALDH1A1MEN1 | |
| SCHEMBL29638552 | 0.64 | MGLL (0.38) | MAPTALDH1A1HPGDMEN1CYP1A2 | |
| SCHEMBL22737499 | 0.63 | KDM4E (0.61) | MAPTKDM4ENSD2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |