Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 12/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557320 | 1.00 | PDE2A (0.36) | PDE2ATYK2CACNA1HPIK3C3PDE1A | |
| SCHEMBL29638472 | 0.87 | POLB (0.39) | TYK2IDH1PIK3CAPRKDC | |
| SCHEMBL29638350 | 0.86 | PHGDH (0.36) | TYK2PIK3CAPRKDC | |
| SCHEMBL24557356 | 0.86 | PHGDH (0.36) | TYK2PIK3CAPRKDC | |
| SCHEMBL29638416 | 0.85 | TYK2 (0.40) | TYK2PIK3C3 | |
| SCHEMBL24557269 | 0.85 | TYK2 (0.40) | TYK2PIK3C3 | |
| SCHEMBL24557297 | 0.84 | BTK (0.39) | — | |
| SCHEMBL29638456 | 0.84 | BTK (0.39) | — | |
| SCHEMBL29638468 | 0.82 | TRPV1 (0.39) | TYK2 | |
| SCHEMBL24557313 | 0.82 | CYP11B1 (0.35) | TYK2PIK3C3PDE4DPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |