Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 12/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557269 | 1.00 | TYK2 (0.40) | TYK2JAK1KCNH2HTTSCN9A | |
| SCHEMBL29638376 | 0.89 | TYK2 (0.40) | TYK2JAK1ALDH1A1 | |
| SCHEMBL27199230 | 0.89 | TYK2 (0.40) | TYK2JAK1ALDH1A1 | |
| SCHEMBL29638340 | 0.88 | TYK2 (0.36) | TYK2JAK1 | |
| SCHEMBL29638471 | 0.86 | IDH1 (0.34) | TYK2JAK1ALDH1A1 | |
| SCHEMBL24557320 | 0.85 | PDE2A (0.36) | TYK2PIK3C3 | |
| SCHEMBL29638430 | 0.85 | PDE2A (0.36) | TYK2PIK3C3 | |
| SCHEMBL29638448 | 0.85 | JAK1 (0.41) | TYK2JAK1HTTSCN9A | |
| SCHEMBL29638329 | 0.84 | FGFR4 (0.36) | TYK2KCNH2ALDH1A1 | |
| SCHEMBL24557292 | 0.84 | TYK2 (0.36) | TYK2JAK1PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |