Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 9/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638419 | 0.89 | TRPV1 (0.50) | ABL1EGFRERBB4TRPV1 | |
| SCHEMBL24557310 | 0.87 | PIK3CD (0.46) | DEGS1ABL1MAP4K1 | |
| SCHEMBL29638393 | 0.87 | GSK3B (0.45) | ABL1 | |
| SCHEMBL24557275 | 0.87 | GSK3B (0.45) | ABL1 | |
| SCHEMBL29638385 | 0.86 | ABL1 (0.47) | DEGS1ABL1MAP4K1 | |
| SCHEMBL29638459 | 0.83 | ABL1 (0.55) | ABL1MEN1KMT2A | |
| SCHEMBL24557312 | 0.83 | MAP4K1 (0.48) | ABL1MAP4K1 | |
| SCHEMBL29638351 | 0.83 | MAP4K1 (0.48) | ABL1MAP4K1 | |
| SCHEMBL24557299 | 0.81 | MAP4K1 (0.46) | ABL1MEN1KMT2AMAP4K1 | |
| SCHEMBL29638359 | 0.81 | KDR (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |