Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.49 |
| ▸ | BRAF | P15056 | 4/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 13/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638393 | 0.90 | GSK3B (0.45) | KDRBRAFGSK3B | |
| SCHEMBL24557275 | 0.90 | GSK3B (0.45) | KDRBRAFGSK3B | |
| SCHEMBL29638382 | 0.87 | ABL1 (0.53) | GSK3B | |
| SCHEMBL29638419 | 0.87 | TRPV1 (0.50) | KDRBRAFSLC5A1 | |
| SCHEMBL24557247 | 0.85 | ABL1 (0.48) | GSK3B | |
| SCHEMBL29638385 | 0.84 | ABL1 (0.47) | GSK3B | |
| SCHEMBL29638461 | 0.81 | DEGS1 (0.51) | — | |
| SCHEMBL29638418 | 0.80 | ABL1 (0.44) | GSK3B | |
| SCHEMBL29638459 | 0.79 | ABL1 (0.55) | GSK3B | |
| SCHEMBL29638399 | 0.79 | BTK (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |