Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 14/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638382 | 0.90 | ABL1 (0.53) | ABL1GSK3BKMT2AMEN1 | |
| SCHEMBL24557310 | 0.87 | PIK3CD (0.46) | ABL1GSK3B | |
| SCHEMBL29638393 | 0.87 | GSK3B (0.45) | ABL1GSK3B | |
| SCHEMBL24557275 | 0.87 | GSK3B (0.45) | ABL1GSK3B | |
| SCHEMBL29638385 | 0.86 | ABL1 (0.47) | ABL1GSK3B | |
| SCHEMBL29638461 | 0.83 | DEGS1 (0.51) | ABL1KMT2AMEN1 | |
| SCHEMBL29638373 | 0.83 | MAP4K1 (0.48) | ABL1GSK3B | |
| SCHEMBL29638418 | 0.82 | ABL1 (0.44) | ABL1GSK3BKMT2AMEN1 | |
| SCHEMBL29638378 | 0.82 | TYK2 (0.46) | ABL1GSK3BKMT2AMEN1 | |
| SCHEMBL24557299 | 0.81 | MAP4K1 (0.46) | ABL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |