Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 4/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.53 |
| ▸ | EGFR | P00533 | 4/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23624398 | 0.86 | TNF (0.75) | TNFABCG2EGFRCLK1LCK | |
| SCHEMBL23624399 | 0.85 | TNF (0.62) | TNFABCG2EGFRCLK1LCK | |
| SCHEMBL29638533 | 0.84 | NCOA1 (0.60) | TNFEGFRLCKMEN1KMT2A | |
| SCHEMBL23624526 | 0.82 | TNF (0.78) | TNFEGFRLCK | |
| SCHEMBL29638557 | 0.81 | PIK3CA (0.51) | TNFMEN1KMT2APIK3CA | |
| SCHEMBL13686770 | 0.77 | MAPK1 (0.56) | TNFABCG2EGFRMEN1KMT2A | |
| SCHEMBL26373508 | 0.77 | ABCG2 (0.51) | TNFABCG2EGFRCLK1LCK | |
| SCHEMBL5564473 | 0.76 | EGFR (0.76) | ABCG2EGFRCLK1LCKMEN1 | |
| SCHEMBL26928619 | 0.75 | TNF (0.48) | TNFLCKPIK3CAKDM4EMAPT | |
| SCHEMBL23624389 | 0.74 | ABL1 (0.49) | TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |